Micro Dosing Pumps for Efficient Sample Preparation

26 Feb 2025  |
Before the analysis of viruses, bacteria, or various blood parameters can begin in an automated analyzer, the sample must first be prepared. Typically, just a few microliters of a solution containing chemicals and enzymes are added to the sample to enable the examination of the sample content.

Sample preparation is a crucial step in diagnostic analytics. This is especially true in molecular biology diagnostics, such as PCR (Polymerase Chain Reaction) or immunological analysis, where precise and reproducible dosing is essential. Even the smallest deviations can affect the sensitivity and specificity of the analysis, leading to inaccurate results.

What are the decision criteria for pumps in this application?

  • High dosing accuracy – Essential for precise results
  • Reproducibility – Consistent and reliable dosing for stable results
  • Wide range of material – Suitable for various media
  • Compact design – Easy integration into laboratory devices and automation systems
  • Low-pulsation and low-shear delivery – Ideal for sensitive sample materials
  • Low maintenance requirements – Robust design ensures a long pump life

These criteria are met by micro dosing pumps from HNP Mikrosysteme GmbH. The mzr-2921 and mzr-4622 pumps from the low-pressure series are used. The minimum dosing quantity is 0.25 μl, the pumps have a very small footprint and can be easily integrated into control systems. Fully automated analysis devices can contain up to sixteen dosing pumps and can handle up to 4,000 samples in 24 hours.

In modern laboratory analytics, precise and reproducible sample preparation is essential. By using mzr-pumps in sample preparation, laboratory workflows can be optimized, sources of error minimized, and quality of analytical data significantly improved. These pumps are ideal for integration into analyzers or open pipetting systems, making them perfect for automated laboratory processes.

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HNP Mikrosysteme develops, manufactures and markets pumps worldwide. These micro annular gear pumps (mzr® pumps) are ideally used where fast and highly precise dosage is required. mzr® pumps make conventional applications more effective, open up...

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